Target species
Pre-ruminant calves.
Indications for use
For the treatment of diarrhoea in pre-ruminant calves associated with infections caused by organisms known to be, or suspected of being, susceptible to the combination of sulfadiazine and neomycin.
Contra-indications
Do not use in animals with known hypersensitivity to the active ingredient.
Do not exceed the recommended dosage or the period of treatment.
Do not use local anaesthetics of the procaine group during treatment as they are antagonistic to the sulphonamide component.
Do not use in calves with a functional rumen.
Do not use in lactating cows.
Do not use in foals and horses.
Special warnings for each target species
Concurrent intravenous fluid therapy should be considered in dehydrated calves. Parenteral antibiotic treatment should be considered if a clinical response is not seen after 48 hours treatment.
Special precautions for use
Special precautions for use in animals
Official, national and regional antimicrobial policies should be taken into account when the product is used.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Care should be taken to avoid contact with the skin. Wash hands after use. Sulphonamides may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to sulphonamides may lead to cross reaction with other antibiotics. Allergic reaction to these substances may occasionally be serious.
1. Do not handle this product if you know you are sensitive to sulphonamides.
2. If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning.
Adverse reactions
Chronic usage of oral neomycin may result in bacterial or fungal superinfections.
Use during pregnancy, lactation or lay
The product is intended for use in calves only.
Do not use in lactating cows.
Interactions
There is interaction and antagonism between sulphonamides and the Vitamin B Complex. Do not use local anaesthetics of the procaine group during treatment, as they are antagonistic to the sulphonamide component.
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Category
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POM-V
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Temperature
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Ambient
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MA/VM/EU No:
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50146/4022
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Species
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VMD Link
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https://www.vmd.defra.gov.uk/productinformationdatabase/files/SPC_Documents/SPC_184403.PDF
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NOAH Link
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Dosage
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Amounts to be administered and administration route
Shake the bottle well before use.
Administration is by oral drench.
4 ml per 10 kg bodyweight twice daily for a maximum period of 5 days. This equates to 60 mg/kg Sulfadiazine and 10 mg/kg Neomycin twice daily. To ensure correct dosage, body weight should be determined as accurately as possible to avoid underdosing.
Overdose
Good tolerance has been confirmed in calves at x3 and x5 times the recommended dose rate.
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Withdrawals
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Withdrawal periods
Meat & offal: 28 days. Not intended for use in animals producing milk for human consumption.
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