Category: Prescriptions
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| Category | POM-VPS |
| Temperature | Refrigerated |
| MA/VM/EU No: | 42058/4022 |
| Species |
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| VMD Link | https://www.vmd.defra.gov.uk/ProductInformationDatabase/product/A005538 |
| NOAH Link | https://www.noahcompendium.co.uk/?id=-456751 |
| Dosage | Dose Sheep – from 2 weeks of age Dose – 1 ml Cattle – from 2 weeks of age Dose – 2 ml Basic vaccination scheme: Two doses should be administered, 4-6 weeks apart. Re-vaccination scheme: A single dose should be administered every 6 to 12 months after the basic vaccination scheme. Administration By subcutaneous injection at a suitable site. The recommended site is the loose skin on the side of the neck. The bottle should be well shaken before any vaccine is withdrawn. Syringes and needles should be sterile before use and the injection should be made through an area of clean, dry skin taking precautions against contamination. Use in pregnancy: To provide passive protection of the offspring, via the colostrum, a single booster dose should be administered between 8 and 2 weeks before parturition, provided that animals have received a full primary vaccination course before pregnancy. |
| Withdrawals | Do not use in sick or immunodeficient animals. Vaccinate healthy animals only. No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis. Do not mix with any other veterinary medicinal product. In the event of an anaphylactic reaction appropriate treatment such as adrenaline should be administered without delay. Very commonly, animals vaccinated with Covexin 10 may experience reactions to vaccination. These reactions are usually localised swelling, induration or other reaction in the underlying tissue at the injection site (very commonly) but may also include mild hyperthermia (very commonly). Swelling at the injection site occurs very commonly. This swelling may reach up to a mean value of 6 cm in diameter in sheep and 15 cm in diameter in cattle; though some cattle reactions of up to 25 cm in diameter may be observed. Most local reactions resolve in 3-6 weeks in sheep and less than 10 weeks in cattle but may persist longer. Commonly, an abscess may develop in some animals. Skin discolouration at the injection site (which returns to normal as the local reaction resolves) may commonly occur. Localised pain at the injection site for 1-2 days post vaccination may occur commonly. The local reactions do not affect the general health, demeanour, feeding or weight gain of the animals. The frequency of adverse reactions is defined using the following convention: -very common (more than 1 in 10 animals treated displaying adverse reaction(s)) -common (more than 1 but less than 10 animals in 100 animals treated) -uncommon (more than 1 but less than 10 animals in 1,000 animals treated) -rare (more than 1 but less than 10 animals in 10,000 animals treated) -very rare (less than 1 animal in 10,000 animals treated, including isolated reports). In calves and lambs, local reactions may increase slightly if twice the recommended dose is administered. No side effects other than those described above were seen when Covexin 10 was used in sheep and cattle between 8 and 2 weeks prior to parturition. In the absence of specific data, no recommendation can be made for use of the vaccine during the first or second trimester of pregnancy. Avoid stress in pregnant ewes and cows. Withdrawal periods Zero days. User Warnings In case of accidental self-injection, seek medical advice immediately showing the package leaflet or the label to the physician. |
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