Online Pet Medications & Pet Supplies

Enrotron Oral 100Mg 1Ltr

   Product Ref: FOENR06 Category: E

£ 158.78


Vat Rate: 20%

Prescription Required



4. CLINICAL PARTICULARS 4.1 Target species Chickens, turkeys, rabbits 4.2 Indications for use, specifying the target species Treatment of infections caused by the following bacteria susceptible to enrofloxacin: Chickens Mycoplasma gallisepticum, Mycoplasma synoviae, Avibacterium paragallinarum, Pasteurella multocida. Turkeys Mycoplasma gallisepticum, Mycoplasma synoviae, Pasteurella multocida. Rabbits For the treatment of infectious diseases due to Pasteurella multocida and bacterial enteritis due to infection with E. coli. Enrofloxacin should be used where clinical experience, supported where possible by sensitivity testing of the causal organism, indicates enrofloxacin as the active substance of choice. 4.3 Contraindications Do not use when resistance / cross-resistance to (fluoro)quinolones is known to occur in the flock intended for treatment. Do not use in cases of known hypersensitivity to the active substance, other (fluoro)quinolones or to any of the excipients. Do not use for prophylaxis. 4.4 Special warnings for each target species Treatment of Mycoplasma spp. infections may not eradicate the organism. 4.5 Special precautions for use Special precautions for use in animals Official and local antimicrobial policies should be taken into account when the product is used. Fluoroquinolones should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials. Since enrofloxacin was first authorised for use in poultry, there has been widespread reduction in susceptibility of E. coli to fluoroquinolones and emergence of resistant organisms. Resistance has also been reported in Mycoplasma synoviae in the EU. Whenever possible fluoroquinolones should only be used based on susceptibility testing. Use of the product deviating from instructions given in the SPC may increase the prevalence of bacteria resistant to fluoroquinolones and may decrease the effectiveness of treatment with other fluoroquinolones due to the potential for cross resistance. Special precautions to be taken by the person administering the veterinary medicinal product to animals People with known hypersensitivity to (fluoro)quinolones should avoid contact with the veterinary medicinal product. Avoid skin and eye contact. Direct contact with the skin should be avoided because of sensitisation, possible hypersensitivity reactions and contact dermatitis. Wear gloves for this purpose. Rinse any splashes from skin or eyes immediately with water. Wash hands and exposed skin after use. Do not eat, drink or smoke whilst using the product. 4.6 Adverse reactions (frequency and seriousness) None known. 4.7 Use during pregnancy, lactation or lay Do not use in laying hens producing eggs for human consumption. Do not administer to layer replacement birds within 14 days of coming into lay. 4.8 Interaction with other medicinal products and other forms of interaction In vitro, an antagonism was shown, when combining fluoroquinolones with bacteriostatic antimicrobial agents such as macrolides or tetracyclines and phenicols. The simultaneous application of substances containing aluminium or magnesium can impair the absorption of enrofloxacin.
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Category POM-V
Temperature Ambient
MA/VM/EU No: 24745/4022
Species
  • chickens
  • rabbits
  • turkeys
VMD Link https://www.vmd.defra.gov.uk/productinformationdatabase/files/SPC_Documents/SPC_493794.PDF
NOAH Link
Dosage 4.9 Amounts to be administered and administration route Chickens and turkeys Via the drinking water. 10 mg enrofloxacin/kg bodyweight per day for 3–5 consecutive days. Treatment for 3–5 consecutive days; for 5 consecutive days in mixed infections and chronic progressive forms. If no clinical improvement is achieved within 2–3 days, alternative antimicrobial therapy should be considered based on susceptibility testing. Always make sure that the entire dose offered has been consumed. The medicated water should be made up fresh each day just before it is offered to the animals. The drinking water must be medicated throughout the treatment period, and no other water source should be available. Determine the bodyweight of the birds as accurately as possible in order to avoid underdosing. Use only fresh pre-solutions, prepared every day before start of treatment. Pumping systems should be checked constantly to assure proper medication. Empty the water system and fill it with medicated water before starting the treatment. Calculate the daily quantity (ml) of the product required for treatment period as follows: Total number of birds x Average body weight in kg x 0.1 = Total volume (ml) per day The product may be put directly into the header tank or introduced via a water proportioner pump. Rabbits 10 mg/kg bodyweight per day for 5 consecutive days. Calculate the daily quantity (ml) of the product required for treatment period as follows: Total number of rabbits x Average body weight in kg x 0.1 = Total volume (ml) per day Medicated drinking water should be replaced every 24 hours. 4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary No adverse clinical symptoms were observed in chickens and turkeys treated respectively with doses up to 10 and 6 times higher than the therapy dose. The use of fluoroquinolones during the growth phase combined with a marked and prolonged increase in the intake of drinking water, and hence active ingredient, possibly due to high temperatures, may potentially be associated with damage of the articular cartilage.
Withdrawals 4.11 Withdrawal period(s) Chickens: Meat and offal: 7 days Turkeys: Meat and offal: 13 days Rabbits: Meat and offal: 15 days Not authorised for use in birds producing eggs for human consumption. Do not administer to layer replacement birds within 14 days of coming into lay.