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Genta Equine 10% Injection 100Ml

   Product Ref: ARGEN01 Category: G

£ 111.98


Vat Rate: 20%

Prescription Required



Target species Horses (non food producing horses). Indications for use For the treatment of infections of the lower respiratory tract in horses caused by aerobic Gram-negative bacteria susceptible to gentamicin. Contraindications Do not use in known cases of renal dysfunction. Do not use in cases of known hypersensitivity to the active substance or to any of the excipients. Do not exceed the proposed dosing regimen. Special warnings for each target species Do not use in horses which are intended to produce meat or milk for human consumption. Special precautions for use in animals Horses: Gentamicin is well known to induce nephrotoxicity even at therapeutic doses. There are also isolated reports of ototoxicity with gentamicin. No margin of safety has been established under the approved dosing regimen. As such, gentamicin has a narrow margin of safety. The product should therefore only be used based on the benefit:risk assessment by the responsible veterinary surgeon for each individual horse, taking into account alternative available treatment. In order to reduce the nephrotoxic risk, adequate hydration of animals under treatment should be ensured, and fluid therapy should be instituted, if required. Close monitoring of horses being treated with gentamicin is strongly advised. This monitoring includes assessing relevant kidney parameters in blood (e.g. creatinine and urea) and urinalysis (e.g. gamma glutamyl transferase/creatinine ratio). Therapeutic blood monitoring of gentamicin concentration is also recommended because of known individual animal variations in peak and trough gentamicin plasma concentrations. Where blood monitoring is available, target peak plasma gentamicin concentrations should be approximately 16-20
Vat Rate: 20%

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Category POM-V
Temperature Ambient
MA/VM/EU No: 33848/4000
Species
  • horses
VMD Link https://www.vmd.defra.gov.uk/productinformationdatabase/files/SPC_Documents/SPC_254343.PDF
NOAH Link
Dosage Amounts to be administered and administration route Horses: Intravenous use. Single dose of 6.6 mg/kg body weight given intravenously once daily for 3-5 consecutive days. To ensure a correct dosage, body weight should be determined as accurately as possible to avoid under or overdosing. The dosing regimen must not be exceeded. The use of gentamicin in foals and neonates is not recommended. Overdose The product was not specifically tested in overdose studies and therefore, no margin of safety has been determined.
Withdrawals Withdrawal periods Not authorised for use in horses producing meat or milk for human consumption.
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