Product Ref: APHYP03 Category: H
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Category | POM-V |
Temperature | Refrigerated |
MA/VM/EU No: | 27569/4004 |
Species |
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VMD Link | https://www.vmd.defra.gov.uk/productinformationdatabase/files/SPC_Documents/SPC_617385.PDF |
NOAH Link | |
Dosage | Amounts to be administered and administration route For intramuscular or intravenous use. Cows For all indications: 3.0 – 5.0 ml/animal, corresponding to 210 – 350 µg carbetocin/animal Sows For shortening of total parturition duration as a part of the synchronisation of parturi-tion: 0.5 ml/animal, corresponding to 35 µg carbetocin/animal For acceleration or restart of parturition after disruption of uterine contractions (uter-ine atony or inertia) following the expulsion of at least one piglet: 0.5 -1.0 ml/animal, corresponding to 35 - 70 µg carbetocin/animal For MMA and milk ejection: 1.5 – 3.0 ml/animal, corresponding to 105 – 210 µg carbetocin/animal The dosage requirements can be variable within the indicated limits based on the assessment of the veterinarian. In case of treatment for milk ejection in the cow and sow or supportive therapy in MMA-syndrome in sow, a repeated administration is possible after 1 to 2 days. The interval between two injections should not be shorter than 24 hours. For all other indications stated in section 4.2 [indications] the product should be ad-ministered once. The rubber stopper of the vial may be safely punctured up to 25 times. Otherwise, automatic syringe equipment, or a suitable draw-off needle, should be used for the 20 and 50 ml vials to avoid excessive puncturing of the closure. 4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary An overdosing of more than 400 µg of carbetocin/animal could increase the stillbirth rate in older sows if administered during prolonged parturition. An overdosing of 600 µg of carbetocin/animal may induce profuse lactation in sows that may result in diarrhoea, reduced weight gain and increased mortality in their piglets. Carbetocin is considered as moderately irritant. At the injection sites of treated ani-mals, focal lymphocytic infiltration was observed at higher doses (1000 µg of car-betocin/animal). |
Withdrawals | Cattle, pigs Meat and offal: Zero days Cattle Milk: Zero hours |