Indications for use, specifying the target species
In cats: treatment of mixed infections by immature and adult cestodes and nematodes of the following species:
Cestodes: Dipylidium caninum, Taenia spp., Echinococcus multilocularis
Nematodes: Ancylostoma tubaeforme, Toxocara cati
Prevention of heartworm disease (Dirofilaria immitis) if concomitant treatment against cestodes is indicated.
Contraindications
Do not use in cats of less than 6 weeks of age and/or weighing less than 0.5 kg.
Do not use in cases of hypersensitivity to the active substances or to any of the excipients.
Special warnings for each target species
It is recommended to treat all the animals living in the same household concomitantly.
In order to develop an effective worm control programme local epidemiological information and the risk of exposure of the cat should be taken into account.
When D. caninum infection is present, concomitant treatment against intermediate hosts, such as fleas and lice, should be considered to prevent re-infection.
Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.
Special precautions for use
Special precautions for use in animals
No studies have been performed with severely debilitated cats or individuals with seriously compromised kidney or liver function. The product is not recommended for such animals or only according to a benefit/risk assessment by the responsible veterinarian.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
People with known hypersensitivity to the active substances or the excipients should avoid contact with the veterinary medicinal product.
In the event of accidental ingestion of the tablets, particularly by a child, seek medical advice immediately and show the package leaflet or the label to the doctor.
Wash hands after use.
Other precautions
Echinococcosis represents a hazard for humans. As echinococcosis is a notifiable disease to the World Organisation for Animal Health (OIE), specific guidelines on the treatment and follow-up, and on the safeguard of persons, need to be obtained from the relevant competent authority.
Adverse reactions (frequency and seriousness)
On very rare occasions, especially in young cats, systemic signs (such as lethargy), neurological signs (such as ataxia and muscle tremors) and/or gastrointestinal signs (such as emesis and diarrhoea) have been observed after administration of the combination milbemycin/praziquantel.
Use during pregnancy, lactation or lay
The veterinary medicinal product can be used in breeding cats including pregnant and lactating queens.
Interaction with other medicinal products and other forms of interaction
The concurrent use of the milbemycin oxime and praziquantel with selamectin is well tolerated. No interactions were observed when the recommended dose of the macrocyclic lactone selamectin was administered during treatment with milbemycin oxime and praziquantel at the recommended dose. In the absence of further studies, caution should be taken in the case of concurrent use of the product and other macrocyclic lactones. Also, no such studies have been performed with reproducing animals.
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Category
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POM-V
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Temperature
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Ambient
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MA/VM/EU No:
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01656/4083
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Species
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VMD Link
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https://www.vmd.defra.gov.uk/productinformationdatabase/files/SPC_Documents/SPC_722209.PDF
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NOAH Link
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Dosage
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Amounts to be administered and administration route
Oral use.
Animals should be weighed to ensure accurate dosing.
Minimum recommended dose rate: 2 mg of milbemycin oxime and 5 mg of praziquantel per kg are given orally as a single dose. The product should be administered with or after some food. Doing so ensures optimum protection against heartworm disease.
Depending on the bodyweight of the cat, the practical dosing is as follows:
Weight
Film-coated tablets for small cats and kittens
0.5 - 1 kg
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Withdrawals
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