PROGRAM PLUS DOG 23-45KG 6 TABS

Target species Dogs Indications for use, specifying the target species PROGRAM Plus is used for the prevention of fleas (Ct. felis, Ct. canis, preadult stages), and for the concurrent prevention of heartworm (elimination of L3/L4 larval stages of Dirofilaria immitis) and/or treatment of adult stages of gastrointestinal nematodes such as hookworms (Ancylostoma caninum), roundworms (Toxocara canis) and whipworms (Trichuris vulpis). Contraindications Do not use in case of hypersensitivity to the active substance, to the adjuvants or to any of the excipients. Special warnings Ideally, tablets are administered on the same day each month. If an interval is greater than 6 weeks, treatment should be resumed immediately and be continued at monthly intervals and, in case of heartworm prevention, a veterinarian should be consulted. Special precautions for use i)Special precautions for use in animals In heartworm risk regions, or in case it is known that a dog has been travelling to and from heartworm risk regions, before commencing PROGRAM Plus treatment as with any other heartworm preventive, a veterinary consultation is advised to exclude the presence of any concurrent infestation of Dirofilaria immitis. In the case of a positive diagnosis, adulticidal therapy is indicated before administering PROGRAM Plus. ii)Special precautions to be taken by the person administering the veterinary medicinal product to animals None. In the case of accidental ingestion seek medical advice immediately and show the package leaflet or the label to the physician. Adverse reactions (frequency and seriousness) Pale mucous membranes, increased intestinal peristalsis, lethargy, diarrhea have been observed very rarely after treatment. The treatment of dogs with a high number of circulating microfilariae can sometimes lead to the appearance of moderate and transitory hypersensitivity reactions, such as pale mucous membranes, vomiting, laboured breathing, or excessive salivation. These reactions are associated with the release of proteins from dead or dying microfilariae and are not a direct toxic effect of the product. Use during pregnancy, lactation or lay Pregnancy: Can be used during pregnancy. Lactation: Can be used during lactation. Interaction with other medicinal products and other forms of interaction During treatment with PROGRAM Plus, no other antiparasitic macrocyclic lactones should be administered.